A novel treatment strategy with hyperbaric oxygen of chronic osteomyelitis and pseudoarthrosis in a child with congenital hereditary sensory and autonomic neuropathy type 4 congenital insensitivity to pain with anhidrosis syndrome: a case report | Canada Hyperbarics Skip to main content
Case Report J Med Case Rep 2025

A novel treatment strategy with hyperbaric oxygen of chronic osteomyelitis and pseudoarthrosis in a child with congenital hereditary sensory and autonomic neuropathy type 4 congenital insensitivity to pain with anhidrosis syndrome: a case report

Kjellberg A, Gustafsson R, Antonsson P, Hedelin H — J Med Case Rep, 2025

View Original on PubMed PMID 39789590
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported the first documented case of a child with congenital insensitivity to pain with anhidrosis (CIPA) treated with HBOT for chronic osteomyelitis and pseudoarthrosis using 40 sessions at 2.4 ATA.

What They Found

The child demonstrated progressive bone healing and resolution of the chronic infection following HBOT. This was the first reported use of HBOT for this combination of conditions in a paediatric patient.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A single paediatric case report cannot generalize to other patients, and the unique nature of CIPA limits applicability.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Report
Category Infection
Source Pubmed
PubMed ID 39789590
Year Published 2025
Journal J Med Case Rep
MeSH Terms Humans; Female; Osteomyelitis; Hyperbaric Oxygenation; Child; Pseudarthrosis; Tibial Fractures; Hereditary Sensory and Autonomic Neuropathies; Anti-Bacterial Agents; Treatment Outcome; Chronic Disease

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology