A rare case of aggressive pyoderma gangrenosum with Cogan syndrome in a person with skin of colour. | Canada Hyperbarics Skip to main content
Clinical Study Skin health and disease 2025

A rare case of aggressive pyoderma gangrenosum with Cogan syndrome in a person with skin of colour.

Nadarajah N, Clark L, Walton S — Skin health and disease, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the case of a 75-year-old South Asian woman diagnosed with aggressive pyoderma gangrenosum associated with atypical Cogan syndrome.

What They Found

They found a 75-year-old South Asian woman presented with aggressive pyoderma gangrenosum (PG) that did not respond to high-dose corticosteroids. Her medical history included recurrent uveitis and bilateral sensorineural deafness, leading to a diagnosis of atypical Cogan syndrome (CS). The patient's PG lesions subsequently healed after treatment with four pulsed cyclophosphamide infusions and hyperbaric oxygen.

Canadian Relevance

This study has no direct Canadian connection as it is a single case report from an unspecified location outside of Canada.

Study Limitations

As a single case report, the findings cannot be generalized to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 40124997
Year Published 2025
Journal Skin health and disease

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology