A survey on the practices and the management of hemorrhagic cystitis in patients who undergo allogeneic hematopoietic stem cell transplantation, on behalf of the Infectious Diseases Working Party of EBMT.

What Researchers Did

Researchers conducted a survey among EBMT centers to understand current practices and management of hemorrhagic cystitis in patients undergoing allogeneic hematopoietic stem cell transplantation.

What They Found

The survey had a 27% response rate, with 93% of centers having BK polyomavirus (BKPyV) diagnostic search available, and 39% performing post-transplant surveillance. Preventative measures mainly involved hyperhydration and Mesna, while primary therapeutic interventions included hyperhydration, Mesna, and analgesics. For BKPyV infection, 85% of centers used intravenous or intrabladder cidofovir.

Canadian Relevance

This study does not have a direct Canadian connection as it focuses on EBMT centers, which are primarily in Europe.

Study Limitations

The survey had a relatively low response rate of 27%, which may limit the generalizability of the findings.