Acute hand ischemia after intra-arterial injection of meprobamate powder. | Canada Hyperbarics Skip to main content
Clinical Study The Journal of emergency medicine 2012

Acute hand ischemia after intra-arterial injection of meprobamate powder.

Seak CK, Kooi XJ, Seak CJ — The Journal of emergency medicine, 2012

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case of acute hand ischaemia in a 23-year-old male drug abuser following accidental intra-arterial injection of crushed meprobamate powder.

What They Found

The 23-year-old patient developed gangrene in the distal tips of his right thumb, index, ring, and little fingers despite various medical therapies including heparinization and hyperbaric oxygen. This is believed to be the first documented human case of acute limb ischaemia caused by intra-arterial injection of meprobamate powder.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case report, the findings are limited in their generalizability to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 22497894
Year Published 2012
Journal The Journal of emergency medicine
MeSH Terms Acute Disease; Adult; Amputation, Surgical; Anti-Inflammatory Agents; Anticoagulants; Dexamethasone; Dextrans; Drug Users; Hand; Humans; Hyperbaric Oxygenation; Hypnotics and Sedatives; Injections, Intra-Arterial; Ischemia; Male

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology