Acute Methaemoglobinaemia as an Overlooked Cause of Acute Dyspnoea in a Patient With Chronic Obstructive Pulmonary Disorder in the Emergency Department | Canada Hyperbarics Skip to main content
Case Report Cureus 2025

Acute Methaemoglobinaemia as an Overlooked Cause of Acute Dyspnoea in a Patient With Chronic Obstructive Pulmonary Disorder in the Emergency Department

Zoaka L, Al-Zoubeidi Z, Khokhar S, Abdelaziz T, Foy-Yamah A — Cureus, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This case report describes a 45-year-old man with chronic obstructive pulmonary disorder (COPD) who developed methaemoglobinaemia after using recreational alkyl nitrates, leading to severe breathing difficulties.

What They Found

The patient presented with worsening shortness of breath and high levels of methaemoglobin in his blood, which were initially missed. His condition was first thought to be an infection-related flare-up of his COPD. The correct diagnosis of methaemoglobinaemia was made only after he revealed his use of recreational alkyl nitrates, leading to treatment including hyperbaric oxygen and ascorbic acid.

What This Means for Canadian Patients

Canadian patients experiencing sudden severe shortness of breath, especially those with existing lung conditions like COPD, should be aware that methaemoglobinaemia can be a hidden cause. This case highlights the importance of a complete medical history, including recreational substance use, for accurate diagnosis. Hyperbaric oxygen therapy, alongside other treatments, can be a vital intervention for this condition.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a case report, this study describes the experience of a single patient, meaning its findings may not apply to all individuals with similar conditions.

Was this summary helpful?

Study Details

Study Type Case Report
Category Uncategorised
Source Pubmed
PubMed ID 41098271
Year Published 2025
Journal Cureus

Cite This Study

Share

Find a Canadian Clinic Treating Uncategorised

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.