What Researchers Did
Researchers conducted a randomised controlled trial to evaluate the effect of adjunctive hyperbaric oxygen therapy after thrombolysis on left ventricular function in patients with acute myocardial infarction.
What They Found
In 74 patients, adjunctive hyperbaric oxygen (HBO+) significantly decreased end-systolic volume index from 30.40 to 28.18 mL/m2, while it increased in the control group (30.89 to 36.68 mL/m2) over three weeks (P <.05). Ejection fraction improved from 46.27% to 50.81% in the HBO+ group, contrasting with a decrease from 45.54% to 44.05% in the control group (P <.05).
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
The study's relatively small sample size of 74 patients and short follow-up period of three weeks limit the generalizability of the findings.