Adjunctive Hyperbaric Oxygen Therapy for Patients with Chronic Refractory Osteomyelitis: A Report of Treatment Outcomes and Risk Factors for Treatment Failure | Canada Hyperbarics
Review Adv Skin Wound Care 2025

Adjunctive Hyperbaric Oxygen Therapy for Patients with Chronic Refractory Osteomyelitis: A Report of Treatment Outcomes and Risk Factors for Treatment Failure

Jackson J, Bakaes Y, Jacques B, Gauthier C, Mills W, Nguyen K, et al. — Adv Skin Wound Care, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers assessed adjunctive HBOT outcomes in 58 patients with chronic refractory osteomyelitis who completed a full course of treatment.

What They Found

Patients who completed the full HBOT course had 7.76 times higher odds of clinical improvement compared to those who did not complete treatment. Overall improvement rates were significantly higher in the HBOT group than in historical controls.

What This Means for Canadian Patients

Chronic osteomyelitis is a debilitating bone infection that often fails conventional antibiotic and surgical treatment. This study supports completing full HBOT courses, which is relevant for Canadian patients undergoing treatment at specialized centres.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

Retrospective design and selection bias in treatment completion may inflate the observed treatment effect.

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Study Details

Study Type Review
Category Infection
Source Pubmed
PubMed ID 39836555
Year Published 2025
Journal Adv Skin Wound Care
MeSH Terms Humans; Osteomyelitis; Hyperbaric Oxygenation; Male; Female; Retrospective Studies; Middle Aged; Risk Factors; Aged; Treatment Failure; Treatment Outcome; Chronic Disease; Adult; Anti-Bacterial Agents; Logistic Models; Combined Modality Therapy

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.