Adjunctive treatment with hyperbaric oxygen in a patient with rhino-sinuso-orbital mucormycosis. | Canada Hyperbarics Skip to main content
Clinical Study Medicina 1991

Adjunctive treatment with hyperbaric oxygen in a patient with rhino-sinuso-orbital mucormycosis.

Melero M, Kaimen Maciel I, Tiraboschi N, Botargues M, Radisic M — Medicina, 1991

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a single insulin-dependent diabetic patient with rhino-sinuso-orbital mucormycosis who received aggressive surgical debridement, increased amphotericin B, and adjunctive hyperbaric oxygen after initial treatments failed.

What They Found

After initial treatments failed, the patient received an additional 3900 mg of amphotericin B (totaling 6800 mg) and adjunctive hyperbaric oxygen. This combined approach led to a successful outcome with no evidence of relapse after 16 months.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case report, the findings of this study cannot be generalized to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 1921693
Year Published 1991
Journal Medicina
MeSH Terms Adult; Amphotericin B; Brain Diseases; Combined Modality Therapy; Debridement; Diabetes Mellitus, Type 1; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Mucormycosis; Nose Diseases

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology