Adjuncts to preparing wounds for closure: hyperbaric oxygen, growth factors, skin substitutes, negative pressure wound therapy (vacuum-assisted closure).

What Researchers Did

This review article discusses various adjunctive treatments, including hyperbaric oxygen, growth factors, skin substitutes, and negative pressure wound therapy, for preparing chronic wounds for closure.

What They Found

This review article identifies that achieving chronic wound closure requires adequate oxygen delivery, nutrition, a moist environment, and appropriate inflammatory conditions. It suggests that adjunctive treatments like hyperbaric oxygen, growth factors, skin substitutes, and negative pressure wound therapy can help establish these necessary conditions for healing in selected patients.

What This Means for Canadian Patients

Canadian patients suffering from chronic wounds may benefit from a range of adjunctive therapies to improve healing outcomes. These treatments could help prepare their wounds for closure by optimizing the local wound environment.

Canadian Relevance

This study has no specific Canadian connection.

Study Limitations

As a review article, this summary synthesizes existing knowledge without presenting new experimental data or specific patient outcomes from a primary study.