What Researchers Did
Researchers conducted a review of existing literature to evaluate the therapeutic use and effects of oxygen, particularly hyperoxia, as a drug.
What They Found
They found that hyperoxia, or high partial pressures of oxygen, has an extensive profile of physiologic and pharmacologic effects, including improved tissue oxygenation, anti-inflammatory and antibacterial actions, and augmented tissue repair mechanisms. Compelling evidence suggests therapeutic potential in conditions like myocardial revascularization, brain insults, and prevention of surgical site infections, indicating oxygen can be a cost-effective and safe drug when carefully administered.
Canadian Relevance
This review did not include any specific Canadian data or research.
Study Limitations
A key limitation is the narrow margin of safety between effective and potentially toxic doses of oxygen, requiring careful control and adherence to protocols.