Bifemelane in the treatment of central retinal artery or vein obstruction | Canada Hyperbarics Skip to main content
Study Clin Ther 1990

Bifemelane in the treatment of central retinal artery or vein obstruction

Hirayama Y, Matsunaga N, Tashiro J, Amemiya T, Iwasaki M — Clin Ther, 1990

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated how well the drug bifemelane, given with or without other treatments, improved vision in patients with blockages in their eye's blood vessels.

What They Found

Patients receiving bifemelane showed improved visual acuity in 12 of 17 eyes (70.6%) with central retinal artery obstruction, compared to 2 of 6 eyes (33.3%) in those not receiving bifemelane. For central retinal vein obstruction, 3 of 4 eyes (75%) improved with bifemelane, while 14 of 27 eyes (51.9%) improved without it. The study concluded that bifemelane can improve vision for many patients with central retinal artery obstruction.

What This Means for Canadian Patients

This study suggests that bifemelane, a drug not widely available in Canada, might help improve vision for patients experiencing blockages in their retinal blood vessels. While hyperbaric oxygen therapy was mentioned as a possible co-treatment in some cases, this study did not provide specific details or outcomes related to HBOT itself. Canadian patients with these conditions should discuss all available treatment options with their ophthalmologist.

Canadian Relevance

No direct Canadian connection identified. This study was not conducted in Canada, nor does it feature Canadian authors. Retinal artery or vein obstruction is not a Health Canada-recognized indication for hyperbaric oxygen therapy.

Study Limitations

The study's main limitation is the varied "other treatment" received by patients, which makes it difficult to isolate the specific effect of bifemelane or any single co-intervention like hyperbaric oxygen therapy.

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Study Details

Study Type Study
Category Ocular / Retinal
Source Pubmed
PubMed ID 2379227
Year Published 1990
Journal Clin Ther
MeSH Terms Adolescent; Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Female; Humans; Male; Middle Aged; Retinal Artery Occlusion; Retinal Vein Occlusion; Visual Acuity

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.