Bisphosphonate-related osteonecrosis of the jaw around dental implants in the maxilla: report of a case. | Canada Hyperbarics Skip to main content
Clinical Study Clinical oral implants research 2009

Bisphosphonate-related osteonecrosis of the jaw around dental implants in the maxilla: report of a case.

Shirota T, Nakamura A, Matsui Y, Hatori M, Nakamura M, Shintani S — Clinical oral implants research, 2009

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described a case of bisphosphonate-related osteonecrosis of the jaw around dental implants in the maxilla of a 54-year-old woman.

What They Found

A 54-year-old woman, who received intravenous bisphosphonates for 2 years for breast cancer bone metastases, developed ONJ around maxillary implants. After surgical resection of the sequestrum and implants, and hyperbaric oxygen therapy, her wound healed completely with no ONJ recurrence during a 6-month follow-up, though she later died from metastatic disease.

Canadian Relevance

This study has no direct Canadian connection as it is a single case report from Japan.

Study Limitations

The primary limitation of this study is its design as a single case report, which prevents generalization of the findings to a broader patient population.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 19793318
Year Published 2009
Journal Clinical oral implants research
MeSH Terms Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Dental Implants; Diphosphonates; Female; Humans; Jaw Diseases; Maxilla; Middle Aged; Osteonecrosis; Radiography

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology