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Clinical Study Vascular medicine (London, England) 1998

Calciphylaxis: a favorable outcome with hyperbaric oxygen.

Dean SM, Werman H, Vascular medicine (London, England), 1998

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Doctors described the case of a 66-year-old woman with diabetes and kidney failure who developed calciphylaxis, a condition where small blood vessels harden and cause painful skin ulcers, and was treated with hyperbaric oxygen after other treatments did not help enough.

What They Found

This case report describes one patient whose leg ulcers had failed to improve significantly despite wound debridement, antibiotics, and surgical removal of part of her parathyroid gland, after which she received hyperbaric oxygen therapy. Testing before treatment showed high calcium x phosphorus levels and high parathyroid hormone, and a biopsy confirmed small vessel calcification in the affected tissue. After 7 weeks of hyperbaric oxygen treatments, her ulcers had essentially healed. No information on the number of sessions per week or the pressure (ATA) used is given in the abstract.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a single case report with no comparison group, and the patient also received debridement, antibiotics, and parathyroidectomy beforehand, so the healing cannot be attributed to hyperbaric oxygen alone.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 9796074
Year Published 1998
Journal Vascular medicine (London, England)
MeSH Terms Aged; Calciphylaxis; Female; Humans; Hyperbaric Oxygenation; Leg Ulcer; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology