Retrospective Study Retinal cases & brief reports 2021

CASE SERIES OF HYPERBARIC OXYGEN THERAPY FOR CENTRAL RETINAL ARTERY OCCLUSION.

Masters TC, Westgard BC, Hendriksen SM, Decanini A, Abel AS, Logue CJ, et al. — Retinal cases & brief reports, 2021

View Original on PubMed PMID 31306292

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively reviewed charts of 39 patients with central retinal artery occlusion (CRAO) who received hyperbaric oxygen (HBO) therapy at a single center.

What They Found

Of 39 patients, 28 (72%) showed some improvement in visual acuity, with a mean improvement of 5.05 lines on a modified Snellen chart after 10 HBO treatments. Patients treated within 12 hours of symptom onset experienced the greatest improvement, averaging 6.11 lines.

Canadian Relevance

This study has no direct Canadian connection as it was conducted at a single hospital center outside of Canada.

Study Limitations

This retrospective, single-center case series has limitations including its observational design and lack of a control group.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type	Retrospective Study
Category	Ocular / Retinal
Source	Pubmed
PubMed ID	31306292
Year Published	2021
Journal	Retinal cases & brief reports
MeSH Terms	Humans; Hyperbaric Oxygenation; Retinal Artery Occlusion; Retrospective Studies

Related Research

Undersea Hyperb Med | 2018 Clinical Study

Effect of hyperbaric oxygen treatment in central retinal artery occlusion

Bagli BS, Cevik SG, Cevik MT.

Clin Ophthalmol | 2021 Clinical Guideline

Hyperbaric oxygen therapy for central retinal artery occlusion: patient selection and perspectives

Celebi ARC, Kiener H.

Korean J Ophthalmol | 2022 Meta-Analysis

The Effects of Hyperbaric Oxygen Therapy in Patients with Central Retinal Artery Occlusion: A Retrospective Study, Systematic Review, and Meta-analysis

Rosignoli L, Chu E, Carter J, Johnson D, Sohn J, Bahadorani S

J Clin Med | 2026 Meta-Analysis

Hyperbaric Oxygen Therapy Versus Intravenous Thrombolysis in the Treatment of Central Retinal Artery Occlusion: A Systematic Review and Meta-Analysis

Bakdalieh A, Siddiqui D, Chen D, Yu M

Minerva Anestesiol | 2001 RCT

Lipid peroxidation, circulating cytokine and endothelin 1 levels in healthy volunteers undergoing hyperbaric oxygenation

Rocco M, Antonelli M, Letizia V, Alampi D, Spadetta G, Passariello M, et al.

See all Ocular / Retinal research

View on PubMed Back to Research Library

Find a Canadian Clinic Treating Ocular / Retinal

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology