Catastrophic vision loss from radiation-induced optic neuropathy. | Canada Hyperbarics Skip to main content
Clinical Study BMJ case reports 2020 Canadian

Catastrophic vision loss from radiation-induced optic neuropathy.

Aldrees S, Micieli JA — BMJ case reports, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report of a 68-year-old woman who developed severe vision loss following radiation therapy for a craniopharyngioma.

What They Found

They found that a 68-year-old woman developed profound vision loss, progressing from hand motion in the right eye and light perception in the left eye to no light perception in both eyes, 9 months after receiving 54 Gy of radiation for a craniopharyngioma. This vision loss occurred over 2 months in the right eye and 1 week in the left, ultimately becoming irreversible despite high-dose corticosteroids, 19 sessions of hyperbaric oxygen therapy, and 3 doses of intravenous bevacizumab.

Canadian Relevance

This case report was authored by Canadian researchers, highlighting a significant clinical challenge within the Canadian healthcare context.

Study Limitations

The primary limitation of this study is its nature as a single case report, which limits the generalizability of its findings to a broader patient population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 32107259
Year Published 2020
Journal BMJ case reports
MeSH Terms Age Factors; Aged; Craniopharyngioma; Female; Humans; Magnetic Resonance Imaging; Optic Nerve; Optic Nerve Diseases; Radiation Dosage; Radiotherapy; Vision Disorders

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This study relates to Delayed Radiation Injury. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology