Catheter-Assisted Application of Hyaluronidase Combined With Multimodal Treatment After Hyaluronic Acid-Induced Ischemia of the Upper Extremity | Canada Hyperbarics Skip to main content
Case Report Aesthet Surg J Open Forum 2025

Catheter-Assisted Application of Hyaluronidase Combined With Multimodal Treatment After Hyaluronic Acid-Induced Ischemia of the Upper Extremity

Hasiba-Pappas S, Kamolz L, Brodmann M, Schweiger L, Pal A, Rappl T, et al. — Aesthet Surg J Open Forum, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described the case of a 62-year-old woman who developed severe arm and hand ischemia after a hyaluronic acid injection and was successfully treated with a combination of therapies, including hyperbaric oxygen therapy.

What They Found

The patient received 6000 units of intra-arterial hyaluronidase, 1500 units subcutaneously, and hyperbaric oxygen therapy for three weeks. This combined treatment led to full restoration of blood flow in her upper extremity, with no long-term complications observed.

What This Means for Canadian Patients

This case suggests a potential multi-modal treatment approach for severe vascular complications following hyaluronic acid injections, which can cause tissue damage and loss of function. While this is a single case, it highlights the importance of prompt and comprehensive treatment, including therapies like HBOT, to restore blood flow and prevent permanent injury.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a single case report, this study's findings cannot be generalized to a larger patient population and require further investigation through larger studies.

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Study Details

Study Type Case Report
Category Aging & Longevity
Source Pubmed
PubMed ID 40626108
Year Published 2025
Journal Aesthet Surg J Open Forum

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.