Clinical Study Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 2023

Comparison of hyperbaric oxygen and ozone treatment for ischemia/re-perfusion injury in an experimental testicular torsion model.

Karlı G, Erginel B, Yanar F, Aycan Üstyol E, Ozluk Y, Savran Karadeniz M, et al. — Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2023

View Original on PubMed PMID 36880629

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared hyperbaric oxygen (HBO) and medical ozone (MO) therapies in an experimental rat model of testicular torsion to assess their effects on oxidative stress and tissue damage.

What They Found

Both HBO and MO treatments significantly decreased malondialdehyde (MDA) levels, indicating reduced oxidative effects, and increased antioxidant glutathione peroxidase (GSH-Px) levels compared to control groups. Hyperbaric oxygen therapy additionally showed a significantly higher increase in superoxide dismutase (SOD) levels compared to all other groups, suggesting a superior antioxidant effect.

Canadian Relevance

This study has no direct Canadian connection or involvement.

Study Limitations

A key limitation is that this was an experimental study conducted on rats, limiting direct generalizability to human patients.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Cardiac
Source	Pubmed
PubMed ID	36880629
Year Published	2023
Journal	Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
MeSH Terms	Animals; Humans; Male; Rats; Antioxidants; Hyperbaric Oxygenation; Ischemia; Oxidants; Oxygen; Ozone; Perfusion; Rats, Wistar; Spermatic Cord Torsion

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology