Comparison of the therapeutic effects in patients with venous leg ulcers treated with routine therapy supplemented by topical hyperbaric oxygen therapy or routine therapy only, basing on the measurement of selected inflammatory markers and blood coagulation parameters: a retrospective study. | Canada Hyperbarics Skip to main content
Retrospective Study Postepy dermatologii i alergologii 2025

Comparison of the therapeutic effects in patients with venous leg ulcers treated with routine therapy supplemented by topical hyperbaric oxygen therapy or routine therapy only, basing on the measurement of selected inflammatory markers and blood coagulation parameters: a retrospective study.

Pasek J, Szajkowski S, Cieślar G — Postepy dermatologii i alergologii, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively compared the therapeutic effects of routine therapy alone versus routine therapy supplemented by topical hyperbaric oxygen therapy (HBOT) in 57 patients with venous leg ulcers.

What They Found

They found that after treatment, the ulcer area in patients receiving topical HBOT (Group 1) was statistically significantly smaller (7.12 cm²) compared to those receiving routine therapy only (Group 2) (8.98 cm²). This comprehensive therapy, including topical HBOT, demonstrated a more effective anti-inflammatory effect without significantly influencing blood coagulation parameters.

What This Means for Canadian Patients

Canadian patients with venous leg ulcers might benefit from the addition of topical hyperbaric oxygen therapy to their routine treatment, potentially leading to improved wound healing. This supplementary therapy could offer a practical approach to enhance anti-inflammatory effects and reduce ulcer size.

Canadian Relevance

No direct Canadian connection was mentioned in the study metadata or abstract.

Study Limitations

As a retrospective study with a relatively small sample size, these findings may be subject to selection bias and limit generalizability.

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Study Details

Study Type Retrospective Study
Category Wound Care
Source Pubmed
PubMed ID 41256057
Year Published 2025
Journal Postepy dermatologii i alergologii

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.