What Researchers Did
This systematic review compared various treatments for bone marrow edema syndrome or transient osteoporosis in middle-aged men and non-pregnant women.
What They Found
Researchers analyzed 36 articles covering 880 patients with bone marrow edema syndrome/transient osteoporosis. They found that bisphosphonates were more effective for pain relief in under one month, while iloprost was better at 1-3 months compared to bisphosphonates and core decompression. At 6-12 months, core decompression and extracorporeal shockwave therapy showed excellent pain relief, followed by bisphosphonates and conservative treatments.
Canadian Relevance
No direct Canadian connection identified.
Study Limitations
The findings are based on a synthesis of existing studies, which may have varied in their design and quality.