Comparison of various treatment modalities for the management of bone marrow edema syndrome/transient osteoporosis in men and non-pregnant women: a systematic review | Canada Hyperbarics Skip to main content
Systematic Review Osteoporos Int 2023

Comparison of various treatment modalities for the management of bone marrow edema syndrome/transient osteoporosis in men and non-pregnant women: a systematic review

Paraskevopoulos K, Keskinis A, Vasios I, Makiev K, Tilkeridis K, Drosos G, et al. — Osteoporos Int, 2023

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

This systematic review compared various treatments for bone marrow edema syndrome or transient osteoporosis in middle-aged men and non-pregnant women.

What They Found

Researchers analyzed 36 articles covering 880 patients with bone marrow edema syndrome/transient osteoporosis. They found that bisphosphonates were more effective for pain relief in under one month, while iloprost was better at 1-3 months compared to bisphosphonates and core decompression. At 6-12 months, core decompression and extracorporeal shockwave therapy showed excellent pain relief, followed by bisphosphonates and conservative treatments.

What This Means for Canadian Patients

This review helps Canadian patients and their doctors understand the effectiveness of various treatments like bisphosphonates, iloprost, core decompression, and extracorporeal shockwave therapy for bone marrow edema syndrome. It provides insights into which treatments might be more effective at different stages of pain resolution for this condition. Patients experiencing this self-limited condition can discuss these findings with their healthcare providers to make informed decisions about their care.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

The findings are based on a synthesis of existing studies, which may have varied in their design and quality.

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Study Details

Study Type Systematic Review
Category Systematic Reviews
Source Pubmed
PubMed ID 36370218
Year Published 2023
Journal Osteoporos Int
MeSH Terms Male; Middle Aged; Humans; Female; Iloprost; Bone Marrow; Bone Marrow Diseases; Pain; Diphosphonates; Edema; Syndrome; Osteoporosis; Multicenter Studies as Topic

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.