Compromised breast flap treated with leech therapy, hyperbaric oxygen, pentoxifylline and topical nitroglycerin: A case report. | Canada Hyperbarics Skip to main content
Case Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 2015

Compromised breast flap treated with leech therapy, hyperbaric oxygen, pentoxifylline and topical nitroglycerin: A case report.

Moffat AD, Weaver LK, Tettelbach WH — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case of a 34-year-old female who developed a compromised breast flap after reduction mammoplasty, which was successfully treated with a combination of leech therapy, hyperbaric oxygen, topical nitroglycerin, and pentoxifylline.

What They Found

The patient initially received topical nitroglycerin, oral pentoxifylline, and hyperbaric oxygen (HBO2), showing some improvement after the first HBO2 session. Leech therapy was then added, with leeches applied three times daily for three days, alongside HBO2 twice daily for six days, leading to complete flap healing by Week 8 without further surgery.

What This Means for Canadian Patients

This multi-modal approach could be a potential option for Canadian patients experiencing compromised surgical flaps, especially in breast reconstruction, to prevent flap failure. It suggests that combining conventional and less conventional therapies might offer a salvage pathway for at-risk flaps, potentially avoiding additional surgeries.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

As a single case report, the findings cannot be generalized to a larger patient population and require further investigation.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 26152110
Year Published 2015
Journal Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms Adult; Animals; Anti-Bacterial Agents; Ceftriaxone; Combined Modality Therapy; Female; Graft Survival; Humans; Hyperbaric Oxygenation; Leeching; Mammaplasty; Nipples; Nitroglycerin; Pentoxifylline; Pigmentation Disorders

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.