Cost-Effectiveness of Continuously Diffused Oxygen Therapy Compared with Negative-Pressure Wound Therapy. | Canada Hyperbarics Skip to main content
Prospective Study Journal of health economics and outcomes research 2026

Cost-Effectiveness of Continuously Diffused Oxygen Therapy Compared with Negative-Pressure Wound Therapy.

Mercurio M, Lavery LA, Agarwal A, Oropallo A — Journal of health economics and outcomes research, 2026

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers prospectively analyzed clinical and real-world billing data from 764 patients to compare the cost-effectiveness of continuous diffusion of oxygen (CDO) therapy versus negative-pressure wound therapy (NPWT) for wound healing.

What They Found

The study found that continuous diffusion of oxygen (CDO) therapy resulted in an average cost savings of US $14,238 per wound compared to negative-pressure wound therapy (NPWT) in the US. CDO also achieved 79.2% full wound closure in 112 days, significantly higher than NPWT's 43.2% closure rate within the same period. These cost savings were demonstrated across two healthcare systems using three methodologies.

What This Means for Canadian Patients

This research suggests that continuous diffusion of oxygen therapy could offer a more effective and potentially cost-saving treatment option for Canadian patients with various types of wounds. Implementing CDO therapy might lead to faster wound healing and reduced healthcare expenditures, improving patient outcomes and resource allocation.

Canadian Relevance

This study was conducted in the US and does not have a direct Canadian connection.

Study Limitations

A limitation is that the study's cost-effectiveness findings are based on US healthcare systems, which may not directly translate to the Canadian context.

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Study Details

Study Type Prospective Study
Category Wound Care
Source Pubmed
PubMed ID 41694478
Year Published 2026
Journal Journal of health economics and outcomes research

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.