Craniocervical Osteoradionecrosis Treated with Neoadjuvant and Adjuvant Hyperbaric Oxygen in Combination with Posterior Spinal Fusion. | Canada Hyperbarics Skip to main content
Clinical Study World neurosurgery 2019

Craniocervical Osteoradionecrosis Treated with Neoadjuvant and Adjuvant Hyperbaric Oxygen in Combination with Posterior Spinal Fusion.

West JL, Frenkel MB, Renfrow JJ, Wilson JA — World neurosurgery, 2019

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on two cases of craniocervical osteoradionecrosis treated with neoadjuvant and adjuvant hyperbaric oxygen therapy combined with posterior spinal fusion.

What They Found

Both patients, who underwent posterior occipital-cervical fusions with an average operative time of 301 minutes and 250 mL blood loss, stayed in the hospital for 5 days without periprocedural complications. Outcomes included a 30% improvement in global assessment of function, solid bony fusion on imaging, and both patients returned to full work duty.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.

Study Limitations

A significant limitation of this study is its very small sample size, reporting on only two cases.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 30858001
Year Published 2019
Journal World neurosurgery
MeSH Terms Adult; Atlanto-Occipital Joint; Cervical Vertebrae; Combined Modality Therapy; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Osteoradionecrosis; Spinal Fusion; Treatment Outcome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology