Current Role of the Nonsteroid Treatment of Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL): A Narrative Review. | Canada Hyperbarics Skip to main content
Clinical Guideline Journal of clinical medicine 2025

Current Role of the Nonsteroid Treatment of Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL): A Narrative Review.

Rodríguez-Izquierdo C, Herrera M, Avdiyuk A, Rodríguez-Ocaña D, Plaza G — Journal of clinical medicine, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a narrative review to evaluate current non-steroid treatment options for idiopathic sudden sensorineural hearing loss (ISSNHL).

What They Found

The review highlighted that systematic steroids are commonly used as first-line treatment for ISSNHL due to their anti-inflammatory effects. However, significant controversy persists regarding the efficacy of steroids and alternative non-steroid treatments like hyperbaric oxygen therapy, N-acetylcysteine, and defibrinogenation therapy.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a narrative review, this study may be subject to selection bias in the included literature and does not provide a systematic analysis of evidence.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Guideline
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 40283640
Year Published 2025
Journal Journal of clinical medicine

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This study relates to Sudden Sensorineural Hearing Loss. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology