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Case Study Wounds : a compendium of clinical research and practice 2015

Deep Frostbite Treated With Hyperbaric Oxygen and Thrombolytic Therapies.

Higdon B, Youngman L, Regehr M, Chiou A — Wounds : a compendium of clinical research and practice, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case of deep frostbite treated with both hyperbaric oxygen and thrombolytic therapies.

What They Found

A patient sustained deep frostbite across 6 digits after becoming intoxicated and unconscious in a snowy field. Despite receiving experimental hyperbaric oxygen and thrombolytic therapies, one digit required partial amputation, and another developed protracted osteomyelitis.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

As a single case study, the findings are not generalizable to a broader patient population.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 26284375
Year Published 2015
Journal Wounds : a compendium of clinical research and practice
MeSH Terms Adult; Amputation, Surgical; Anti-Bacterial Agents; Fibrinolytic Agents; Frostbite; Humans; Hyperbaric Oxygenation; Male; Osteomyelitis; Oxygen; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology