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Clinical Study Brain & development 2007

Delayed neuropsychiatric syndrome in a child following carbon monoxide poisoning.

Kondo A, Saito Y, Seki A, Sugiura C, Maegaki Y, Nakayama Y, et al. — Brain & development, 2007

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported the case of a five-year-old boy who developed delayed neuropsychiatric syndrome following carbon monoxide poisoning.

What They Found

A five-year-old boy initially recovered from carbon monoxide (CO) poisoning after hyperbaric oxygen (HBO) therapy, but developed lethargy, visual and gait disturbances two days later, followed by left hemiparesis and mood lability. MRI revealed high signal-intensity lesions in the hippocampus and cerebral cortex initially, with globus pallidum lesions at 14 days and cortical laminar necrosis at 4 months. While neurological symptoms gradually subsided during 10 days of HBO, left-hand paresis, quadrantic hemianopsia, impaired attention, slow mental processing, and incontinence persisted.

Canadian Relevance

This study has no direct Canadian connection as it reports a case from Japan.

Study Limitations

As a single case report, the findings of this study may not be generalizable to all children experiencing delayed neuropsychiatric syndrome after carbon monoxide poisoning.

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Study Details

Study Type Clinical Study
Category Carbon Monoxide Poisoning
Source Pubmed
PubMed ID 17008041
Year Published 2007
Journal Brain & development
MeSH Terms Carbon Monoxide Poisoning; Child, Preschool; Feeding and Eating Disorders; Hemianopsia; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Male; Mental Disorders; Paresis; Thyrotropin-Releasing Hormone; Tomography, Emission-Computed, Single-Photon; Vision Disorders

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology