Diagnosis of an Acinetobacter pittii from a patient in China with a multiplex PCR-based targeted gene sequencing platform of the cerebrospinal fluid: A case report with literature review | Canada Hyperbarics Skip to main content
Case Report Medicine (Baltimore) 2022

Diagnosis of an Acinetobacter pittii from a patient in China with a multiplex PCR-based targeted gene sequencing platform of the cerebrospinal fluid: A case report with literature review

Feng W, Jiang X, Zhang R, Guo Z, Gao D — Medicine (Baltimore), 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers in China used a new gene sequencing platform to diagnose a rare bacterial infection in the cerebrospinal fluid of a 49-year-old male patient who developed acute purulent meningoencephalitis.

What They Found

A 49-year-old Chinese male developed acute purulent meningoencephalitis after a subarachnoid hemorrhage and subsequent craniotomies. Initial cerebrospinal fluid smear and routine culture tests were negative, but a multiplex PCR-based targeted gene sequencing platform (ptNGS) successfully identified *Acinetobacter pittii* and *Staphylococcus epidermidis* as the pathogens.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

As a case report, this study's findings are based on a single patient and may not apply to a broader population.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Case Report
Category Uncategorised
Source Pubmed
PubMed ID 36281177
Year Published 2022
Journal Medicine (Baltimore)
MeSH Terms Humans; Male; Middle Aged; Multiplex Polymerase Chain Reaction; Ceftazidime; Vancomycin; Xylose; Valproic Acid; High-Throughput Nucleotide Sequencing; Staphylococcus epidermidis; Mannitol; Acinetobacter

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology