Distal Arterialized Venous Supercharging Improves Perfusion and Survival in an Extended Dorsal Three-Perforasome Perforator Flap Rat Model. | Canada Hyperbarics Skip to main content
Clinical Study Plastic and reconstructive surgery 2021

Distal Arterialized Venous Supercharging Improves Perfusion and Survival in an Extended Dorsal Three-Perforasome Perforator Flap Rat Model.

Wu H, Zhang C, Chen Z, Lou J, Ding J, Wang L, et al. — Plastic and reconstructive surgery, 2021

View Original on PubMed PMID 34019505
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated whether a distal arterialized venous supercharged (DAVS) flap procedure improved perfusion and survival in an extended dorsal three-perforasome perforator flap rat model.

What They Found

The distal arterialized venous supercharged (DAVS) flap group demonstrated a significantly higher survival rate of 100% compared to 81.93 ± 5.38% in the control group (p < 0.001). All measured blood flow ratios, including those in choke zones, were also significantly higher in the DAVS flap group (all p < 0.05).

Canadian Relevance

This study was not conducted in Canada and does not have a direct Canadian connection.

Study Limitations

A primary limitation of this study is its reliance on an animal model, which may not fully translate to human physiology and clinical outcomes.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 34019505
Year Published 2021
Journal Plastic and reconstructive surgery
MeSH Terms Animals; Dermatologic Surgical Procedures; Disease Models, Animal; Graft Survival; Humans; Intraoperative Complications; Ischemia; Male; Perforator Flap; Rats; Skin

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology