Effect of hyperbaric oxygen on a rat transverse rectus abdominis myocutaneous flap model. | Canada Hyperbarics Skip to main content
Clinical Study Plastic and reconstructive surgery 1998

Effect of hyperbaric oxygen on a rat transverse rectus abdominis myocutaneous flap model.

Ramon Y, Abramovich A, Shupak A, Ullmann Y, Moscona RA, Shoshani O, et al. — Plastic and reconstructive surgery, 1998

View Original on PubMed PMID 9703078
Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers compared hyperbaric oxygen therapy to normobaric oxygen, hyperbaric air, and no treatment in preventing transverse rectus abdominis myocutaneous (TRAM) flap necrosis in a rat model.

What They Found

They found that hyperbaric oxygen significantly increased TRAM flap survival to 52.5% compared to 38.5% in the control group (p = 0.05). This treatment protocol resulted in significantly greater flap area survival.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

This study was conducted in a rat model, limiting its direct applicability to human patients.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 9703078
Year Published 1998
Journal Plastic and reconstructive surgery
MeSH Terms Animals; Capillaries; Graft Survival; Humans; Hyperbaric Oxygenation; Male; Necrosis; Neovascularization, Physiologic; Oxygen Consumption; Oxygen Inhalation Therapy; Rats; Rats, Sprague-Dawley; Surgical Flaps; Treatment Outcome

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology