What Researchers Did
Researchers randomly assigned 22 patients with a history of orofacial radiotherapy to either a hyperbaric oxygen therapy (HBOT) group or a control group to evaluate the therapy's effect on vascular function and tissue oxygenation.
What They Found
After HBOT, blood flow in irradiated mucosa and skin significantly increased after heat provocation (P < 0.05), and tissue oxygenation (TcPO2) significantly improved in the irradiated cheek (P < 0.05).
These beneficial effects persisted for at least 6 months, with no significant changes observed in the control group.
What This Means for Canadian Patients
Canadian patients who have received radiotherapy to the face or mouth may experience improved blood flow and oxygenation in the affected tissues with hyperbaric oxygen therapy.
This could potentially aid in the healing and overall health of irradiated skin and gums, with effects lasting for several months.
Canadian Relevance
This study has no direct Canadian connection as it was conducted in Norway.
Study Limitations
The study's relatively small sample size of 22 patients may limit the generalizability of its findings.