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Pilot Study Diving and hyperbaric medicine 2022

Effect of hyperbaric oxygen treatment on skin elasticity in irradiated patients.

Pandey K, Teguh DN, van Hulst RA — Diving and hyperbaric medicine, 2022

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers measured skin elasticity, using skin retraction time, in 13 irradiated breast cancer patients before and after hyperbaric oxygen treatment (HBOT) to quantify its effects on late radiation-induced tissue fibrosis.

What They Found

The mean irradiated skin retraction time significantly improved from 417 msec pre-HBOT to 171 msec post-HBOT (P < 001). Conversely, the mean pre-HBOT retraction time in non-irradiated skin was 143 msec and did not change after treatment. This pilot study suggests HBOT may improve skin elasticity in patients with late radiation-induced tissue fibrosis.

What This Means for Canadian Patients

Canadian patients experiencing late radiation-induced tissue fibrosis after breast cancer treatment might find hyperbaric oxygen therapy beneficial for improving skin elasticity. This could potentially help manage some of the long-term skin changes and discomfort following radiation.

Canadian Relevance

This study does not have a direct Canadian connection.

Study Limitations

This was a pilot study with a small sample size of only 13 patients, limiting the generalizability of the findings.

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Study Details

Study Type Pilot Study
Category Radiation Injury
Source Pubmed
PubMed ID 36100932
Year Published 2022
Journal Diving and hyperbaric medicine
MeSH Terms Adult; Aged; Elasticity; Humans; Hyperbaric Oxygenation; Middle Aged; Oxygen; Pilot Projects; Radiation Injuries

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.