Effect of hyperbaric oxygenation on normalization of intestinal function after surgical treatment of Hirschsprung disease and anorectal developmental defects in children.

What Researchers Did

Researchers performed 264 hyperbaric oxygenation (HBO) procedures in 93 children who underwent surgery for Hirschsprung's disease and anorectal developmental defects.

What They Found

The study observed a positive effect of hyperbaric oxygenation (HBO) on postoperative complications in 93 children. HBO improved intestinal wall viability, stabilized peristalsis, and reduced gastric fluid retention and anaerobic infection risk. This approach also shortened parenteral nutrition duration and decreased purulent-septic complications.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada or by Canadian researchers.

Study Limitations

A significant limitation is the absence of a randomised control group, which makes it difficult to definitively attribute the observed positive effects solely to hyperbaric oxygenation.