Case Report Adv Skin Wound Care 2026

Effective Treatment of Nicolau Syndrome Induced by Etofenamate Injection Using Hyperbaric Oxygen Therapy

Kurmuş G, Şensoy Söğüt D, Menteşoğlu D, Tatar S, Kartal S — Adv Skin Wound Care, 2026

View Original on PubMed PMID 41159779

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case of Nicolau syndrome -- a rare injection-site necrosis complication -- treated with 30 sessions of HBOT following failed conventional wound management.

What They Found

HBOT promoted progressive wound healing and prevented surgical amputation in the affected limb. The patient achieved significant tissue recovery after completing the treatment course.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

A single case report cannot establish efficacy; outcomes may not generalize to other patients or injection sites.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Case Report
Category	Wound Care
Source	Pubmed
PubMed ID	41159779
Year Published	2026
Journal	Adv Skin Wound Care
MeSH Terms	Humans; Hyperbaric Oxygenation; Female; Middle Aged; Nicolau Syndrome; Injections, Intramuscular; Anti-Inflammatory Agents, Non-Steroidal; Osteoarthritis, Knee; Wound Healing; Treatment Outcome

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: March 19, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology