Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a systematic review with meta-analysis and trial sequential analysis. | Canada Hyperbarics Skip to main content
Meta-Analysis BMJ open 2020

Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a systematic review with meta-analysis and trial sequential analysis.

Vinkel J, Holm NFR, Jakobsen JC, Hyldegaard O — BMJ open, 2020

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers developed a protocol for a systematic review and meta-analysis to assess the beneficial and harmful effects of adding hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers.

What They Found

As this is a protocol for a systematic review, no direct findings or numerical results are presented in this document. The researchers plan to include all relevant randomized clinical trials, assessing primary outcomes like all-cause mortality, serious adverse events, and quality of life, and secondary outcomes such as healing of index wound, major amputation, and wound infection. The protocol was developed following Cochrane Collaboration recommendations and an eight-step assessment procedure.

What This Means for Canadian Patients

As this is a protocol, there are no immediate implications for Canadian patients; however, the future systematic review will provide evidence on hyperbaric oxygen therapy for diabetic foot ulcers. This evidence could inform treatment guidelines and improve care for Canadian patients suffering from this major health problem.

Canadian Relevance

This study protocol has no direct Canadian connection.

Study Limitations

As a protocol, this document does not present completed research or definitive findings, but rather outlines the methodology for a future systematic review.

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Study Details

Study Type Meta-Analysis
Category Wound Care
Source Pubmed
PubMed ID 32601110
Year Published 2020
Journal BMJ open
MeSH Terms Diabetic Foot; Humans; Hyperbaric Oxygenation; Meta-Analysis as Topic; Research Design; Systematic Reviews as Topic; Wound Healing

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.