Retrospective Study Cardiology journal 2018

Effects of hyperbaric oxygen on vascular endothelial function in patients with slow coronary flow.

Li Y, Zhang H, Liang Y, Wang W, Xu T, Zhang J, et al. — Cardiology journal, 2018

View Original on PubMed PMID 29512098

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers retrospectively analyzed 98 patients with slow coronary flow, comparing those who received hyperbaric oxygen therapy plus conventional treatment (n=48) with a control group receiving conventional treatment alone (n=50) over 4 weeks.

What They Found

Before treatment, there were no significant differences in vascular endothelial function markers between the two groups (p > 0.05). After 4 weeks, the hyperbaric oxygen group showed significantly increased flow-mediated vasodilation (FMD) and plasma levels of nitric oxide (NO) and calcitonin gene-related peptide (CGRP) compared to the control group.

Canadian Relevance

This study was conducted in China and has no direct Canadian connection.

Study Limitations

As a retrospective study with a relatively small sample size of 98 patients, the findings may not be broadly generalizable.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Retrospective Study
Category	Cardiac
Source	Pubmed
PubMed ID	29512098
Year Published	2018
Journal	Cardiology journal
MeSH Terms	Adult; Aged; Blood Flow Velocity; Brachial Artery; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Oxygen

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology