Effects of Hyperbaric Oxygen Therapy for Malignant Bowel Obstruction Caused by Peritoneal Dissemination | Canada Hyperbarics Skip to main content
Retrospective Study Kurume Med J 2025

Effects of Hyperbaric Oxygen Therapy for Malignant Bowel Obstruction Caused by Peritoneal Dissemination

Muroya D, Arai S, Nishida T, Ishimaru T, Yamazaki Y, Goto Y, et al. — Kurume Med J, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers conducted a retrospective study of 44 cancer patients with malignant bowel obstruction from peritoneal spread, comparing 30 who received daily HBOT at 2.5 ATA for 60 minutes against 14 who did not.

What They Found

Significantly more HBOT patients resumed eating compared to the non-HBOT group. The proportion with unresolved obstruction was significantly higher in the non-HBOT group. Overall survival was significantly longer in the HBOT group, even among patients who could not have surgery.

What This Means for Canadian Patients

For Canadian cancer patients with bowel obstruction from peritoneal spread who cannot have surgery, HBOT may improve quality of life by restoring the ability to eat and extending survival. This is a palliative care context where few effective options exist.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This is a small retrospective study from a single Japanese center, limiting generalizability and introducing potential selection bias in who received HBOT.

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Study Details

Study Type Retrospective Study
Category Uncategorised
Source Pubmed
PubMed ID 39343579
Year Published 2025
Journal Kurume Med J
MeSH Terms Humans; Hyperbaric Oxygenation; Male; Female; Intestinal Obstruction; Retrospective Studies; Middle Aged; Aged; Peritoneal Neoplasms; Treatment Outcome; Adult; Aged, 80 and over; Prognosis

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.