Effects of Oxygen Therapies in Experimental Acute Acoustic Trauma. | Canada Hyperbarics Skip to main content
Clinical Study The journal of international advanced otology 2021

Effects of Oxygen Therapies in Experimental Acute Acoustic Trauma.

Ata N, Kahraman E, Incesulu A, Yildirim E — The journal of international advanced otology, 2021

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated the effects of normobaric and hyperbaric oxygen therapies on acute acoustic trauma in rats, comparing them to a control group.

What They Found

For frequencies of 3, 4, 5, and 6 kHz, there was a statistically significant difference within time and between groups. Unexpectedly, the control group demonstrated better recovery of distortion product otoacoustic emission values across all frequencies by days 3, 5, and 7 compared to both oxygen therapy groups. While hyperbaric oxygen therapy showed better values than normobaric oxygen therapy by day 3, this trend reversed by days 5 and 7.

Canadian Relevance

This study has no direct Canadian connection as it was conducted by researchers outside of Canada and did not involve Canadian participants or institutions.

Study Limitations

A significant limitation is that this was an experimental study conducted in rats, meaning the findings may not directly translate to human patients.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Sudden Hearing Loss
Source Pubmed
PubMed ID 35177387
Year Published 2021
Journal The journal of international advanced otology
MeSH Terms Animals; Hearing Loss, Noise-Induced; Hearing Loss, Sudden; Humans; Hyperbaric Oxygenation; Otoacoustic Emissions, Spontaneous; Oxygen; Rats

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology