Efficacy of hyperbaric oxygen therapy combine with negative pressure wound therapy in chronic wound: A randomized controlled trial. | Canada Hyperbarics Skip to main content
RCT JPRAS open 2025

Efficacy of hyperbaric oxygen therapy combine with negative pressure wound therapy in chronic wound: A randomized controlled trial.

Riansrithongkham T, Yongchareon P, Sivadechathep A, Likitvong A, Mahamongkol T, Pruksapong C — JPRAS open, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This multicenter randomized controlled trial compared the efficacy of hyperbaric oxygen therapy combined with negative pressure wound therapy versus negative pressure wound therapy alone for chronic wounds.

What They Found

The combined NPWT+HBOT group showed significantly higher wound healing rates compared to the NPWT-only group, with rates of 11.81% vs. 8.54% on day 3, and 20.15% vs. 14.9% on day 12. There were no significant differences observed in pain scores or bacterial contamination between the two groups.

What This Means for Canadian Patients

Canadian patients with chronic wounds might experience faster healing if hyperbaric oxygen therapy is added to their negative pressure wound therapy regimen. This combined approach could potentially reduce the overall time needed for wound care and improve recovery.

Canadian Relevance

This study did not include Canadian participants or researchers, and therefore has no direct Canadian connection.

Study Limitations

The study's relatively small sample size of 24 patients per group and its short duration may limit the generalizability of the findings.

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Study Details

Study Type RCT
Category Wound Care
Source Pubmed
PubMed ID 40502361
Year Published 2025
Journal JPRAS open

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.