Efficacy of hyperbaric oxygen therapy in patients with radiation-induced rectal ulcers: Report of five cases. | Canada Hyperbarics Skip to main content
Clinical Study Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2017

Efficacy of hyperbaric oxygen therapy in patients with radiation-induced rectal ulcers: Report of five cases.

Yoshimizu S, Chino A, Miyamoto Y, Tagao F, Iwasaki S, Ide D, et al. — Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2017

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers assessed the efficacy of hyperbaric oxygen therapy in five patients suffering from radiation-induced rectal ulcers.

What They Found

Significant improvement and complete ulcer resolution were observed in all five treated patients, with no reported side-effects. However, hyperbaric oxygen therapy alone failed to improve telangiectasia and easy bleeding in four of the five patients, who then received additional argon plasma coagulation. These findings suggest that combination therapy with hyperbaric oxygen therapy and argon plasma coagulation may be an effective strategy for radiation-induced rectal ulcers.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

The primary limitation of this study is its very small sample size, involving only five patients, which limits the generalizability of the findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

Was this summary helpful?

Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 28349612
Year Published 2017
Journal Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
MeSH Terms Adult; Aged; Brachytherapy; Dose-Response Relationship, Radiation; Female; Follow-Up Studies; Humans; Hyperbaric Oxygenation; Middle Aged; Proctitis; Radiation Injuries; Radiotherapy Dosage; Radiotherapy, Adjuvant; Rectal Diseases; Sampling Studies

Cite This Study

Share

This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

Find a Canadian Clinic Treating Wound Care

Browse verified hyperbaric facilities across Canada.

View Canadian Facilities

Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology