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Clinical Study Gynecologic oncology 1994

Enterovesical fistula following radiotherapy for gynecologic cancer.

Levenback C, Gershenson DM, McGehee R, Eifel PJ, Morris M, Burke TW — Gynecologic oncology, 1994

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers identified 14 patients who developed enterovesical fistula after pelvic radiotherapy for gynecologic cancer, without tumor recurrence.

What They Found

Among 14 patients with enterovesical fistula following pelvic radiotherapy, six had colovesical, five had enterovesical, and three had both small and large bowel fistulae. Twelve patients underwent 13 surgical procedures, with bowel resection achieving successful repair in 5 of 6 cases, compared to 1 of 3 for diversion and 2 of 4 for isolation. Two of three perioperative deaths occurred in the isolation group managed without urinary conduit.

What This Means for Canadian Patients

Canadian patients undergoing pelvic radiotherapy for gynecologic cancer should be aware of the rare but serious risk of enterovesical fistula, even without tumor recurrence. Surgical intervention, particularly bowel resection, appears to offer the best chance for successful repair and resolution of this complication.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

This study is limited by its small sample size of 14 patients and retrospective design.

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Study Details

Study Type Clinical Study
Category Radiation Injury
Source Pubmed
PubMed ID 8157186
Year Published 1994
Journal Gynecologic oncology
MeSH Terms Adult; Aged; Female; Genital Neoplasms, Female; Humans; Intestinal Fistula; Middle Aged; Radiotherapy; Urinary Bladder Fistula

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.