What Researchers Did
Researchers systematically addressed the ethical concept of clinical equipoise concerning hyperbaric oxygen treatment (HBOT) for necrotising soft tissue infections (NSTI) in the context of a proposed randomised controlled trial.
What They Found
They found that clinical equipoise is a critical ethical consideration for centers contemplating participation in an HBOT randomised controlled trial for NSTI, especially where HBOT is already considered standard practice. The article presented a series of considerations for key stakeholders at potential participating sites to evaluate before joining such a trial.
Canadian Relevance
This study has no direct Canadian connection.
Study Limitations
A limitation is that this article is a conceptual discussion and does not present empirical data or outcomes from an actual clinical trial.