Evaluation and treatment of critical asthma syndrome in children | Canada Hyperbarics Skip to main content
Review Clin Rev Allergy Immunol 2015

Evaluation and treatment of critical asthma syndrome in children

Wade A, Chang C — Clin Rev Allergy Immunol, 2015

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

This systematic review evaluated the distinct features of severe asthma in children and summarized current treatment and management strategies for critical asthma syndrome in paediatric patients.

What They Found

Researchers noted that paediatric asthma differs significantly from adult asthma, often characterized by atopy and stable lung function. Current treatments for severe paediatric asthma include continuous nebulization, intubation, heliox, magnesium sulfate, epinephrine, intravenous immunoglobulin, and montelukast. The study emphasized that preventative treatment is crucial to reduce severe exacerbations, requiring careful selection of individualized therapies and ensuring patient and caregiver compliance.

Canadian Relevance

No direct Canadian connection identified. This study is not Canadian, and while "Hyperbaric Oxygenation" is listed in the MeSH terms, the abstract does not discuss HBOT as a treatment for asthma, which is not a Health Canada-recognised indication for HBOT.

Study Limitations

A key limitation is the inherent variability of asthma, meaning not all patients will respond equally to the same treatment, making individualized therapy selection challenging.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Review
Category Systematic Reviews
Source Pubmed
PubMed ID 24488329
Year Published 2015
Journal Clin Rev Allergy Immunol
MeSH Terms Acetates; Animals; Asthma; Caregivers; Child; Critical Illness; Cyclopropanes; Humans; Hyperbaric Oxygenation; Immunoglobulins, Intravenous; Patient Compliance; Patient Education as Topic; Practice Guidelines as Topic; Quinolines; Respiration, Artificial; Sulfides; Syndrome

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology