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Review Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 2014

Evaluation of hyperbaric oxygen therapy for chronic wounds.

Ueno T, Omi T, Uchida E, Yokota H, Kawana S, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2014

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Doctors reviewed the medical records of patients with hard-to-heal wounds who received hyperbaric oxygen therapy (HBOT) along with standard wound care.

What They Found

This was a retrospective review of 29 patients with chronic wounds from various causes, treated with HBOT at 2.8 atmospheres of absolute pressure for 60 minutes per session using 100% oxygen. The wound response was rated "excellent" in 6 patients, "good" in 8, "fair" in 11, and "poor" in 4. All 4 patients with a "poor" response had diabetes and were undergoing hemodialysis. The wound causes included diabetes (13 patients), venous stasis (10), and several rarer conditions in the remaining patients.

What This Means for Canadian Patients

For Canadians with chronic wounds from diabetes, venous stasis, or other causes, this study suggests outcomes with HBOT added to standard wound care vary widely, from major improvement to no meaningful benefit. Patients with diabetes who are also on hemodialysis appeared to respond poorly in this group, which may be relevant for similar patients considering HBOT. Because this was a records review without a comparison group, it cannot show how these patients would have done with standard wound care alone.

Canadian Relevance

No direct Canadian connection identified.

Study Limitations

This was a small, single-center, retrospective review of 29 patients with no control group, so it cannot prove that HBOT caused the wound improvements seen.

This plain-language summary was generated with AI assistance from the study's abstract; it has not been individually reviewed by a clinician. Always consult the source study and a qualified healthcare professional. See our editorial policy.

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Study Details

Study Type Review
Category Wound Care
Source Pubmed
PubMed ID 24614389
Year Published 2014
Journal Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
MeSH Terms Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Wounds and Injuries

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This study relates to Problem Wounds. Read the full clinical overview, the evidence base, and Canadian treatment access for this condition.

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last updated: April 1, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology