Clinical Study Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc 1995

Experimental retinopathy by hyperbaric oxygenation.

Torbati D, Peyman GA, Wafapoor H, Shaibani SB, Khoobehi B — Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 1995

View Original on PubMed PMID 7742708

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers exposed five- to seven-day-old rats to hyperbaric oxygenation (HBO) or HBO with hypercapnia for five hours, then assessed retinal vascular density two months later.

What They Found

Retinal vascular density (RVD) significantly increased from 0.0112 +/- 0.004 in air-exposed controls to 0.0417 +/- 0.029 in HBO-exposed rats. HBO with hypercapnia resulted in an RVD of 0.0255 +/- 0.007, reducing the HBO-induced increase by 39%.

Canadian Relevance

This study has no direct Canadian connection.

Study Limitations

A significant limitation is that this study was conducted in a rat model, which may not directly translate to human physiology.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type	Clinical Study
Category	Ocular / Retinal
Source	Pubmed
PubMed ID	7742708
Year Published	1995
Journal	Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc
MeSH Terms	Animals; Animals, Newborn; Behavior, Animal; Female; Humans; Hyperbaric Oxygenation; Hypercapnia; Infant, Newborn; Male; Rats; Rats, Sprague-Dawley; Retinopathy of Prematurity; Seizures; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology