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RCT Anesthesiology 2000

Extent of hyperbaric spinal anesthesia influences the duration of spinal block

Kooger Infante N, Van Gessel E, Forster A, Gamulin Z — Anesthesiology, 2000

Tier 1, Curated

Manually reviewed and included in the Canada Hyperbarics research database.

Summary

What Researchers Did

Researchers investigated how the spread of spinal anesthesia affects how long it lasts by injecting a specific dose of hyperbaric bupivacaine into 40 patients undergoing lower limb surgery and positioning them either flat or with their torso elevated.

What They Found

Patients positioned flat had a significantly higher spread of sensory blockade, reaching a median of T3.5 compared to T10 for those with an elevated torso. This wider spread resulted in faster regression of sensory blockade by two segments (216 mm vs. 253 mm) and to segment L4 (269 mm vs. 337 mm). They also experienced quicker recovery from motor blockade (173 mm vs. 233 mm) and an earlier return of pain at the surgical site (221 mm vs. 271 mm).

Canadian Relevance

No direct Canadian connection identified. This study is about spinal anesthesia, not hyperbaric oxygen therapy for Health Canada-recognised indications.

Study Limitations

The study involved a relatively small group of patients undergoing specific lower limb surgeries, which may limit the generalizability of the findings to other patient populations or surgical procedures.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type RCT
Category Uncategorised
Source Pubmed
PubMed ID 10877732
Year Published 2000
Journal Anesthesiology
MeSH Terms Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Hemodynamics; Humans; Hyperbaric Oxygenation; Injections, Spinal; Leg; Male; Middle Aged; Nerve Block; Neuromuscular Blockade; Posture; Time Factors

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 17, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology