Granulomatous amebic encephalitis in a child with acute lymphoblastic leukemia successfully treated with multimodal antimicrobial therapy and hyperbaric oxygen. | Canada Hyperbarics Skip to main content
Clinical Study Journal of clinical microbiology 2011

Granulomatous amebic encephalitis in a child with acute lymphoblastic leukemia successfully treated with multimodal antimicrobial therapy and hyperbaric oxygen.

Maritschnegg P, Sovinz P, Lackner H, Benesch M, Nebl A, Schwinger W, et al. — Journal of clinical microbiology, 2011

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported a case of a child with acute lymphoblastic leukaemia who developed granulomatous amebic encephalitis and was successfully treated.

What They Found

They found that a combination of multimodal antimicrobial chemotherapy and hyperbaric oxygen therapy led to the complete resolution of symptoms. Imaging also showed complete resolution of the brain pathology in the one reported child.

Canadian Relevance

This study has no direct Canadian connection as it was conducted outside of Canada.

Study Limitations

A significant limitation of this study is that it is a single case report, limiting the generalizability of its findings.

This plain-language summary is generated with AI assistance and checked against the source abstract before publication. See our editorial policy.

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Study Details

Study Type Clinical Study
Category Infection
Source Pubmed
PubMed ID 21084511
Year Published 2011
Journal Journal of clinical microbiology
MeSH Terms Acanthamoeba; Amebiasis; Antiprotozoal Agents; Brain; Brain Abscess; Central Nervous System Protozoal Infections; Child, Preschool; DNA, Protozoan; Encephalitis; Humans; Magnetic Resonance Imaging; Male; Molecular Sequence Data; Oxygen; Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology