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Case Study Journal of the American Podiatric Medical Association 2025

Hafnia Alvei on a Diabetic Foot: A Case Report.

Demir B, Birinci M, Catal B — Journal of the American Podiatric Medical Association, 2025

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers presented a case report detailing the diagnosis and management of a severe diabetic foot ulcer caused by the atypical pathogen Hafnia alvei.

What They Found

They found that a long-term diabetic patient presented with a severe grade 4 foot ulcer, where post-treatment cultures surprisingly identified Hafnia alvei and Proteus spp. as causative agents. Despite rigorous antibiotic therapy and debridement, complications led to a Chopart amputation, with the wound completely healed at the 6-month follow-up.

What This Means for Canadian Patients

Canadian patients with diabetic foot ulcers, especially those not responding to standard treatments, should be aware that unusual pathogens might be involved. This highlights the importance of comprehensive diagnostic testing and a multidisciplinary team approach for optimal management and potentially preventing severe outcomes like amputation.

Canadian Relevance

This case report has no direct Canadian connection as it describes a patient treated outside of Canada.

Study Limitations

As a case report, this study's findings are limited by its focus on a single patient, meaning the observations may not be generalizable to the broader diabetic population.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 41166151
Year Published 2025
Journal Journal of the American Podiatric Medical Association
MeSH Terms Female; Humans; Middle Aged; Amputation, Surgical; Anti-Bacterial Agents; Debridement; Diabetic Foot; Gram-Negative Bacterial Infections

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.