Healing of severe perineal and cutaneous Crohn's disease with hyperbaric oxygen. | Canada Hyperbarics Skip to main content
Case Study Gastroenterology 1989

Healing of severe perineal and cutaneous Crohn's disease with hyperbaric oxygen.

Brady CE, Cooley BJ, Davis JC — Gastroenterology, 1989

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers reported on a patient with severe, refractory perineal and cutaneous Crohn's disease treated with hyperbaric oxygen.

What They Found

The patient experienced dramatic relief of symptoms and regression of wounds within 2.5 months, after 8 years of unsuccessful prior therapies. While clinical remission required four subsequent courses of hyperbaric oxygen over 11 months, the patient remained largely asymptomatic with minimal cutaneous disease compared to before treatment.

Canadian Relevance

This study has no direct Canadian connection as it is a case report from a non-Canadian institution.

Study Limitations

As a single case report, the findings cannot be generalized to a broader patient population, and the treatment is noted to be costly and not for routine use.

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Study Details

Study Type Case Study
Category Wound Care
Source Pubmed
PubMed ID 2753335
Year Published 1989
Journal Gastroenterology
MeSH Terms Combined Modality Therapy; Crohn Disease; Female; Humans; Hyperbaric Oxygenation; Metronidazole; Middle Aged; Perineum; Recurrence; Skin Diseases

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology