What Researchers Did
Researchers described the case of a 75-year-old woman with polycythemia vera who developed a large post-operative cutaneous ulcer while on hydroxyurea therapy.
What They Found
The patient, who had been treated with 500mg hydroxyurea daily for six years, developed erythema and necrosis two days after a hernioplasty, which progressed to a 22x15cm ulcer on her lower abdomen. The ulcer significantly decreased in size following the termination of hydroxyurea.
Canadian Relevance
This study has no direct Canadian connection as it describes a case from another country.
Study Limitations
As a single case report, the findings may not be generalizable to all patients taking hydroxyurea.