Hydroxyurea associated leg ulcer succesfully treated with hyperbaric oxygen in a diabetic patient. | Canada Hyperbarics Skip to main content
Clinical Study Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2007

Hydroxyurea associated leg ulcer succesfully treated with hyperbaric oxygen in a diabetic patient.

Akinci B, Yesil S, Atabey A, Ilgezdi S — Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2007

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers described a diabetic patient with a hydroxyurea-associated leg ulcer who was successfully treated with hyperbaric oxygen therapy and general wound care after discontinuing hydroxyurea.

What They Found

They observed faster improvement of the leg ulcer in this diabetic patient compared to outcomes reported in the literature for hydroxyurea withdrawal as a single therapy. This suggests that hyperbaric oxygen therapy, combined with general wound care, may be beneficial for managing hydroxyurea-associated leg ulcers, particularly in diabetic individuals.

Canadian Relevance

This study has no direct Canadian connection as it was not conducted in Canada, nor does it involve Canadian researchers or patient populations.

Study Limitations

A significant limitation of this study is that it describes only a single patient, which limits the generalizability of its findings to a broader population.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 17318777
Year Published 2007
Journal Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
MeSH Terms Diabetes Complications; Diabetes Mellitus, Type 2; Humans; Hydroxyurea; Hyperbaric Oxygenation; Leg Ulcer; Male; Middle Aged; Polycythemia Vera

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology