Hyperbaric oxygen. A new adjunct in the management of radiation necrosis. | Canada Hyperbarics Skip to main content
Clinical Study Archives of otolaryngology (Chicago, Ill. : 1960) 1979

Hyperbaric oxygen. A new adjunct in the management of radiation necrosis.

Davis JC, Dunn JM, Gates GA, Heimbach RD — Archives of otolaryngology (Chicago, Ill. : 1960), 1979

Tier 2, Indexed

Automatically imported from PubMed based on relevance criteria.

Summary

What Researchers Did

Researchers investigated hyperbaric oxygen therapy as an adjunctive treatment for 52 cases of radiation necrosis, with 39 cases involving the head and neck.

What They Found

Among 23 cases of osteoradionecrosis of the mandible, 19 remained arrested for up to two years following hyperbaric oxygen therapy. Additionally, 15 of 16 cases of soft-tissue radionecrosis of the head and neck were successfully managed with this therapy combined with surgery and antibiotics.

Canadian Relevance

The study does not indicate any direct Canadian connection or involvement.

Study Limitations

A limitation of this study is the absence of a control group, which prevents direct comparison of outcomes with and without hyperbaric oxygen therapy.

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Study Details

Study Type Clinical Study
Category Wound Care
Source Pubmed
PubMed ID 760715
Year Published 1979
Journal Archives of otolaryngology (Chicago, Ill. : 1960)
MeSH Terms Adult; Aged; Female; Humans; Hyperbaric Oxygenation; Male; Mandibular Diseases; Middle Aged; Necrosis; Osteoradionecrosis; Radiation Injuries

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Disclaimer: This study summary is provided for informational and educational purposes only. It does not constitute medical advice. The information presented reflects the findings of the original research authors and may not represent the views of Canada Hyperbarics. Always consult a qualified healthcare professional before making treatment decisions.

Last reviewed: April 2, 2026 | Reviewed by: Canada Hyperbarics Editorial Team | Editorial process | Research sources | Counts & methodology